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Global profiling of DNA methylation erasure in mouse primordial germ cells

Epigenetic reprogramming, characterized by loss of cytosine methylation and histone modifications, occurs during mammalian development in primordial germ cells (PGCs), yet the targets and kinetics of this process are poorly characterized. Here we provide a map of cytosine methylation on a large port...

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Detalles Bibliográficos
Main Authors: Guibert, Sylvain, Forné, Thierry, Weber, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317146/
https://ncbi.nlm.nih.gov/pubmed/22357612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.130997.111
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