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Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity
Mouse embryos acquire global DNA methylation of their genome during implantation. However the exact roles of DNA methyltransferases (DNMTs) in embryos have not been studied comprehensively. Here we systematically analyze the consequences of genetic inactivation of Dnmt1, Dnmt3a and Dnmt3b on the met...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7305168/ https://ncbi.nlm.nih.gov/pubmed/32561758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16919-w |
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