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Mutant p53 Drives Cancer by Subverting Multiple Tumor Suppression Pathways
The tumor suppressor p53 normally acts as a brake to halt damaged cells from perpetrating their genetic errors into future generations. If p53 is disrupted by mutation, it may not only lose these corrective powers, but counterproductively acquire new capacities that drive cancer. A newly emerging ma...
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| 發表在: | Front Oncol |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4728204/ https://ncbi.nlm.nih.gov/pubmed/26858938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00012 |
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