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Human Tumor-Derived p53 Mutants: A Growing Family of Oncoproteins
TP53 gene mutations are present in more than half of all human cancers. The resulting proteins are mostly full-length with a single amino acid change and are abundantly expressed in cancer cells. Some of the mutant p53 proteins gain oncogenic functions (GOF) through which it actively contribute to t...
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| Publicado no: | Frontiers Research Topics |
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| Main Authors: | , |
| Formato: | Livro |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media SA
2016
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| Assuntos: | |
| Acesso em linha: | https://directory.doabooks.org/handle/20.500.12854/49645 |
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