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Mutant p53 Drives Cancer by Subverting Multiple Tumor Suppression Pathways

The tumor suppressor p53 normally acts as a brake to halt damaged cells from perpetrating their genetic errors into future generations. If p53 is disrupted by mutation, it may not only lose these corrective powers, but counterproductively acquire new capacities that drive cancer. A newly emerging ma...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Haupt, Sue, Raghu, Dinesh, Haupt, Ygal
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728204/
https://ncbi.nlm.nih.gov/pubmed/26858938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00012
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