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Regulation of Mutant p53 Protein Expression

For several decades, p53 has been detected in cancer biopsies by virtue of its high protein expression level which is considered indicative of mutation. Surprisingly, however, mouse genetic studies revealed that mutant p53 is inherently labile, similar to its wild type (wt) counterpart. Consistently...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Vijayakumaran, Reshma, Tan, Kah Hin, Miranda, Panimaya Jeffreena, Haupt, Sue, Haupt, Ygal
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681805/
https://ncbi.nlm.nih.gov/pubmed/26734569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00284
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