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Regulation of Mutant p53 Protein Expression

For several decades, p53 has been detected in cancer biopsies by virtue of its high protein expression level which is considered indicative of mutation. Surprisingly, however, mouse genetic studies revealed that mutant p53 is inherently labile, similar to its wild type (wt) counterpart. Consistently...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Vijayakumaran, Reshma, Tan, Kah Hin, Miranda, Panimaya Jeffreena, Haupt, Sue, Haupt, Ygal
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681805/
https://ncbi.nlm.nih.gov/pubmed/26734569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00284
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