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Human Tumor-Derived p53 Mutants: A Growing Family of Oncoproteins

TP53 gene mutations are present in more than half of all human cancers. The resulting proteins are mostly full-length with a single amino acid change and are abundantly expressed in cancer cells. Some of the mutant p53 proteins gain oncogenic functions (GOF) through which it actively contribute to t...

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Bibliografske podrobnosti
izdano v:Frontiers Research Topics
Main Authors: Giovanni Blandino, Ygal Haupt
Format: Livro
Jezik:Inglês
Izdano: Frontiers Media SA 2016
Teme:
Online dostop:https://directory.doabooks.org/handle/20.500.12854/49645
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