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The inactivation domain of STIM1 is functionally coupled with the Orai1 pore to enable Ca(2+)-dependent inactivation
The inactivation domain of STIM1 (ID(STIM): amino acids 470–491) has been described as necessary for Ca(2+)-dependent inactivation (CDI) of Ca(2+) release–activated Ca(2+) (CRAC) channels, but its mechanism of action is unknown. Here we identify acidic residues within ID(STIM) that control the exten...
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| 出版年: | J Gen Physiol |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4727943/ https://ncbi.nlm.nih.gov/pubmed/26809794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511438 |
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