A direct role for the Sec1-Munc18-family protein Vps33 as a template for SNARE assembly

Fusion of intracellular transport vesicles requires soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) and Sec1/Munc18-family (SM) proteins. Membrane-bridging SNARE complexes are critical for fusion, but their spontaneous assembly is inefficient and may require SM protei...

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Foilsithe in:Science
Main Authors: Baker, Richard W., Jeffrey, Philip D., Zick, Michael, Phillips, Ben P., Wickner, William T., Hughson, Frederick M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727825/
https://ncbi.nlm.nih.gov/pubmed/26339030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aac7906
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