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The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation

Fusion of intracellular trafficking vesicles is mediated by the assembly of SNARE proteins into membrane-bridging complexes. SNARE-mediated membrane fusion requires Sec1/Munc18-family (SM) proteins, SNARE chaperones that can function as templates to catalyze SNARE complex assembly. Paradoxically, th...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Eisemann, Travis J, Allen, Frederick, Lau, Kelly, Shimamura, Gregory R, Jeffrey, Philip D, Hughson, Frederick M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470827/
https://ncbi.nlm.nih.gov/pubmed/32804076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60724
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