Activation of HIV-1 with Nanoparticle-Packaged Small-Molecule Protein Phosphatase-1-Targeting Compound

Complete eradication of HIV-1 infection is impeded by the existence of latent HIV-1 reservoirs in which the integrated HIV-1 provirus is transcriptionally inactive. Activation of HIV-1 transcription requires the viral Tat protein and host cell factors, including protein phosphatase-1 (PP1). We previ...

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Vydáno v:Sci Pharm
Hlavní autoři: Smith, Kahli A., Lin, Xionghao, Bolshakov, Oleg, Griffin, James, Niu, Xiaomei, Kovalskyy, Dmytro, Ivanov, Andrey, Jerebtsova, Marina, Taylor, Robert E., Akala, Emmanuel, Nekhai, Sergei
Médium: Artigo
Jazyk:Inglês
Vydáno: The Austrian Journal of Pharmaceutical Sciences 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727795/
https://ncbi.nlm.nih.gov/pubmed/26839837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1502-01
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