Reactivation of latent HIV-1 provirus via targeting protein phosphatase-1

BACKGROUND: HIV-1 escapes antiretroviral drugs by integrating into the host DNA and forming a latent transcriptionally silent HIV-1 provirus. This provirus presents the major hurdle in HIV-1 eradication and cure. Transcriptional activation, which is prerequisite for reactivation and the eradication...

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Vydáno v:Retrovirology
Hlavní autoři: Tyagi, Mudit, Iordanskiy, Sergey, Ammosova, Tatyana, Kumari, Namita, Smith, Kahli, Breuer, Denitra, Ilatovskiy, Andrey V, Kont, Yasemin Saygideğer, Ivanov, Andrey, Üren, Aykut, Kovalskyy, Dmytro, Petukhov, Michael, Kashanchi, Fatah, Nekhai, Sergei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504130/
https://ncbi.nlm.nih.gov/pubmed/26178009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0190-4
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