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CDK2 Regulates HIV-1 Transcription by Phosphorylation of CDK9 on Serine 90
BACKGROUND: HIV-1 transcription is activated by the viral Tat protein that recruits host positive transcription elongation factor-b (P-TEFb) containing CDK9/cyclin T1 to the HIV-1 promoter. P-TEFb in the cells exists as a lower molecular weight CDK9/cyclin T1 dimer and a high molecular weight comple...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3515335/ https://ncbi.nlm.nih.gov/pubmed/23140174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-94 |
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