Phosphodiesterase function and endocrine cells: links to human disease and roles in tumor development and treatment

Phosphodiesterases (PDEs) are enzymes that regulate the intracellular levels of cyclic adenosine monophosphate and cyclic guanosine monophosphate, and, consequently, exhibit a central role in multiple cellular functions. The pharmacological exploitation of the ability of PDEs to regulate specific pa...

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Bibliografiske detaljer
Udgivet i:Curr Opin Pharmacol
Main Authors: Levy, Isaac, Horvath, Anelia, Azevedo, Monalisa, de Alexandre, Rodrigo Bertollo, Stratakis, Constantine A
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727450/
https://ncbi.nlm.nih.gov/pubmed/22047791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2011.10.003
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