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Phosphodiesterase function and endocrine cells: links to human disease and roles in tumor development and treatment
Phosphodiesterases (PDEs) are enzymes that regulate the intracellular levels of cyclic adenosine monophosphate and cyclic guanosine monophosphate, and, consequently, exhibit a central role in multiple cellular functions. The pharmacological exploitation of the ability of PDEs to regulate specific pa...
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| Publicado no: | Curr Opin Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4727450/ https://ncbi.nlm.nih.gov/pubmed/22047791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2011.10.003 |
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