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Alterations of Phosphodiesterases in Adrenocortical Tumors

Alterations in the cyclic (c)AMP-dependent signaling pathway have been implicated in the majority of benign adrenocortical tumors (ACTs) causing Cushing syndrome (CS). Phosphodiesterases (PDEs) are enzymes that regulate cyclic nucleotide levels, including cyclic adenosine monophosphate (cAMP). Inact...

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Bibliografski detalji
Izdano u:Front Endocrinol (Lausanne)
Glavni autori: Hannah-Shmouni, Fady, Faucz, Fabio R., Stratakis, Constantine A.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003917/
https://ncbi.nlm.nih.gov/pubmed/27625633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2016.00111
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