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Phosphodiesterase function and endocrine cells: links to human disease and roles in tumor development and treatment

Phosphodiesterases (PDEs) are enzymes that regulate the intracellular levels of cyclic adenosine monophosphate and cyclic guanosine monophosphate, and, consequently, exhibit a central role in multiple cellular functions. The pharmacological exploitation of the ability of PDEs to regulate specific pa...

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Publicat a:Curr Opin Pharmacol
Autors principals: Levy, Isaac, Horvath, Anelia, Azevedo, Monalisa, de Alexandre, Rodrigo Bertollo, Stratakis, Constantine A
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727450/
https://ncbi.nlm.nih.gov/pubmed/22047791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2011.10.003
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