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Integrating mutation and gene expression cross-sectional data to infer cancer progression

BACKGROUND: A major problem in identifying the best therapeutic targets for cancer is the molecular heterogeneity of the disease. Cancer is often caused by an accumulation of mutations which produce irreversible damage to the cell’s control mechanisms of survival and proliferation. Different mutatio...

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Dades bibliogràfiques
Publicat a:BMC Syst Biol
Autors principals: Fleck, Julia L., Pavel, Ana B., Cassandras, Christos G.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727329/
https://ncbi.nlm.nih.gov/pubmed/26810975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0255-6
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