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Integrative modeling of multi-omics data to identify cancer drivers and infer patient-specific gene activity

BACKGROUND: High throughput technologies have been used to profile genes in multiple different dimensions, such as genetic variation, copy number, gene and protein expression, epigenetics, metabolomics. Computational analyses often treat these different data types as independent, leading to an explo...

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Bibliografski detalji
Izdano u:BMC Syst Biol
Glavni autori: Pavel, Ana B., Sonkin, Dmitriy, Reddy, Anupama
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750289/
https://ncbi.nlm.nih.gov/pubmed/26864072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0260-9
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