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Integrating mutation and gene expression cross-sectional data to infer cancer progression

BACKGROUND: A major problem in identifying the best therapeutic targets for cancer is the molecular heterogeneity of the disease. Cancer is often caused by an accumulation of mutations which produce irreversible damage to the cell’s control mechanisms of survival and proliferation. Different mutatio...

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Podrobná bibliografie
Vydáno v:BMC Syst Biol
Hlavní autoři: Fleck, Julia L., Pavel, Ana B., Cassandras, Christos G.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727329/
https://ncbi.nlm.nih.gov/pubmed/26810975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0255-6
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