Amidated and Ibuprofen-Conjugated Kyotorphins Promote Neuronal Rescue and Memory Recovery in Cerebral Hypoperfusion Dementia Model

Chronic brain ischemia is a prominent risk factor for neurological dysfunction and progression for dementias, including Alzheimer’s disease (AD). In rats, permanent bilateral common carotid artery occlusion (2VO) causes a progressive neurodegeneration in the hippocampus, learning deficits and memory...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Sá Santos, Sónia, Santos, Sara M., Pinto, Antónia R. T., Ramu, Vasanthakumar G., Heras, Montserrat, Bardaji, Eduard, Tavares, Isaura, Castanho, Miguel A. R. B.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726799/
https://ncbi.nlm.nih.gov/pubmed/26858637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2016.00001
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