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The Neuroprotective Action of Amidated-Kyotorphin on Amyloid β Peptide-Induced Alzheimer’s Disease Pathophysiology

Kyotorphin (KTP, l-tyrosyl-l-arginine) is an endogenous dipeptide initially described to have analgesic properties. Recently, KTP was suggested to be an endogenous neuroprotective agent, namely for Alzheimer’s disease (AD). In fact, KTP levels were shown to be decreased in the cerebrospinal fluid of...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Belo, Rita F., Martins, Margarida L. F., Shvachiy, Liana, Costa-Coelho, Tiago, de Almeida-Borlido, Carolina, Fonseca-Gomes, João, Neves, Vera, Vicente Miranda, Hugo, Outeiro, Tiago F., Coelho, Joana E., Xapelli, Sara, Valente, Cláudia A., Heras, Montserrat, Bardaji, Eduard, Castanho, Miguel A. R. B., Diógenes, Maria José, Sebastião, Ana M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363954/
https://ncbi.nlm.nih.gov/pubmed/32733240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00985
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