The Neuroprotective Action of Amidated-Kyotorphin on Amyloid β Peptide-Induced Alzheimer’s Disease Pathophysiology

Kyotorphin (KTP, l-tyrosyl-l-arginine) is an endogenous dipeptide initially described to have analgesic properties. Recently, KTP was suggested to be an endogenous neuroprotective agent, namely for Alzheimer’s disease (AD). In fact, KTP levels were shown to be decreased in the cerebrospinal fluid of...

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Veröffentlicht in:Front Pharmacol
Hauptverfasser: Belo, Rita F., Martins, Margarida L. F., Shvachiy, Liana, Costa-Coelho, Tiago, de Almeida-Borlido, Carolina, Fonseca-Gomes, João, Neves, Vera, Vicente Miranda, Hugo, Outeiro, Tiago F., Coelho, Joana E., Xapelli, Sara, Valente, Cláudia A., Heras, Montserrat, Bardaji, Eduard, Castanho, Miguel A. R. B., Diógenes, Maria José, Sebastião, Ana M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363954/
https://ncbi.nlm.nih.gov/pubmed/32733240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00985
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