Inhibition of nociceptive responses after systemic administration of amidated kyotorphin

BACKGROUND AND PURPOSE: Kyotorphin (KTP; L-Tyr-L-Arg), an endogenous neuropeptide, is potently analgesic when delivered directly to the central nervous system. Its weak analgesic effects after systemic administration have been explained by inability to cross the blood–brain barrier (BBB) and detract...

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Bibliographic Details
Main Authors: Ribeiro, MMB, Pinto, A, Pinto, M, Heras, M, Martins, I, Correia, A, Bardaji, E, Tavares, I, Castanho, M
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2011
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130928/
https://ncbi.nlm.nih.gov/pubmed/21366550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01290.x
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