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Inhibition of nociceptive responses after systemic administration of amidated kyotorphin

BACKGROUND AND PURPOSE: Kyotorphin (KTP; L-Tyr-L-Arg), an endogenous neuropeptide, is potently analgesic when delivered directly to the central nervous system. Its weak analgesic effects after systemic administration have been explained by inability to cross the blood–brain barrier (BBB) and detract...

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Dettagli Bibliografici
Autori principali: Ribeiro, MMB, Pinto, A, Pinto, M, Heras, M, Martins, I, Correia, A, Bardaji, E, Tavares, I, Castanho, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130928/
https://ncbi.nlm.nih.gov/pubmed/21366550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01290.x
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