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Hydrolysis of Ibuprofen Nitrile and Ibuprofen Amide and Deracemisation of Ibuprofen Using Nocardia corallina B-276

A novel application of whole cells of Nocardia corallina B-276 for the deracemisation of ibuprofen is reported. This microorganism successfully hydrolysed ibuprofen nitrile to ibuprofen amide, and ibuprofen amide to ibuprofen, using a suspension of cells in a potassium phosphate buffer solution (0.1...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Lievano, Ricardo, Pérez, Herminia Inés, Manjarrez, Norberto, Solís, Aida, Solís-Oba, Myrna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268212/
https://ncbi.nlm.nih.gov/pubmed/22410421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17033148
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