Optimal acquisition and modeling parameters for accurate assessment of low K(trans) blood-brain barrier permeability using dynamic contrast-enhanced MRI

PURPOSE: To determine optimal parameters for acquisition and processing of dynamic contrast-enhanced (DCE) MRI to detect small changes in near normal low blood-brain barrier (BBB) permeability. METHODS: Using a contrast-to-noise ratio metric (K-CNR) for K(trans) precision and accuracy, the effects o...

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Bibliografiset tiedot
Julkaisussa:Magn Reson Med
Päätekijät: Barnes, Samuel R., Ng, Thomas S.C., Montagne, Axel, Law, Meng, Zlokovic, Berislav V., Jacobs, Russell E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726482/
https://ncbi.nlm.nih.gov/pubmed/26077645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.25793
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