Comparison Between Blood-Brain Barrier Water Exchange Rate and Permeability to Gadolinium-Based Contrast Agent in an Elderly Cohort

Background: Dynamic contrast-enhanced (DCE) MRI using intravenous injection of gadolinium-based contrast agents (GBCAs) is commonly used for imaging blood-brain barrier (BBB) permeability. Water is an alternative endogenous tracer with limited exchange rate across the BBB. A direct comparison betwee...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Shao, Xingfeng, Jann, Kay, Ma, Samantha J., Yan, Lirong, Montagne, Axel, Ringman, John M., Zlokovic, Berislav V., Wang, Danny J. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733970/
https://ncbi.nlm.nih.gov/pubmed/33328848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.571480
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