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Alzheimer’s disease: A matter of blood–brain barrier dysfunction?

The blood–brain barrier (BBB) keeps neurotoxic plasma-derived components, cells, and pathogens out of the brain. An early BBB breakdown and/or dysfunction have been shown in Alzheimer’s disease (AD) before dementia, neurodegeneration and/or brain atrophy occur. However, the role of BBB breakdown in...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Montagne, Axel, Zhao, Zhen, Zlokovic, Berislav V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679168/
https://ncbi.nlm.nih.gov/pubmed/29061693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171406
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