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Mapping water exchange across the blood-brain barrier using three-dimensional diffusion-prepared arterial spin labeled perfusion MRI

PURPOSE: To present a novel MR pulse sequence and modeling algorithm to quantify the water exchange rate (k(w)) across the BBB without contrast, and to evaluate its clinical utility in a cohort of elderly subjects at risk of cerebral small vessel disease (SVD). METHODS: A diffusion preparation modul...

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Detalhes bibliográficos
Publicado no:Magn Reson Med
Main Authors: Shao, Xingfeng, Ma, Samantha J, Casey, Marlene, D’Orazio, Lina, Ringman, John M, Wang, Danny JJ
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414249/
https://ncbi.nlm.nih.gov/pubmed/30561821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.27632
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