Optimal acquisition and modeling parameters for accurate assessment of low K(trans) blood-brain barrier permeability using dynamic contrast-enhanced MRI

PURPOSE: To determine optimal parameters for acquisition and processing of dynamic contrast-enhanced (DCE) MRI to detect small changes in near normal low blood-brain barrier (BBB) permeability. METHODS: Using a contrast-to-noise ratio metric (K-CNR) for K(trans) precision and accuracy, the effects o...

Full description

Saved in:
Bibliographic Details
Published in:Magn Reson Med
Main Authors: Barnes, Samuel R., Ng, Thomas S.C., Montagne, Axel, Law, Meng, Zlokovic, Berislav V., Jacobs, Russell E.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726482/
https://ncbi.nlm.nih.gov/pubmed/26077645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.25793
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items