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Distinct mutation accumulation rates among tissues determine the variation in cancer risk

Cancer is believed to be a result of accumulated mutations. However, this concept has not been fully confirmed owing to the impossibility of tracking down the ancestral somatic cell. We sought to verify the concept by exploring the correlation between cancer risk and mutation accumulation among diff...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hao, Dapeng, Wang, Li, Di, Li-jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726417/
https://ncbi.nlm.nih.gov/pubmed/26785814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19458
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