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Mutation Rate Variation is a Primary Determinant of the Distribution of Allele Frequencies in Humans
The site frequency spectrum (SFS) has long been used to study demographic history and natural selection. Here, we extend this summary by examining the SFS conditional on the alleles found at the same site in other species. We refer to this extension as the “phylogenetically-conditioned SFS” or cSFS....
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| Publicado no: | PLoS Genet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5157949/ https://ncbi.nlm.nih.gov/pubmed/27977673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006489 |
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