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Distinct Contributions of Replication and Transcription to Mutation Rate Variation of Human Genomes
Here, we evaluate the contribution of two major biological processes—DNA replication and transcription—to mutation rate variation in human genomes. Based on analysis of the public human tissue transcriptomics data, high-resolution replicating map of Hela cells and dbSNP data, we present significant...
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| Publicado no: | Genomics Proteomics Bioinformatics |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5054443/ https://ncbi.nlm.nih.gov/pubmed/22449396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1672-0229(11)60028-4 |
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