Structural Insights into the Quaternary Catalytic Mechanism of Hexameric Human Quinolinate Phosphoribosyltransferase, a Key Enzyme in de novo NAD Biosynthesis

Quinolinate phosphoribosyltransferase (QPRT) catalyses the production of nicotinic acid mononucleotide, a precursor of de novo biosynthesis of the ubiquitous coenzyme nicotinamide adenine dinucleotide. QPRT is also essential for maintaining the homeostasis of quinolinic acid in the brain, a possible...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Youn, Hyung-Seop, Gyun Kim, Tae, Kim, Mun-Kyoung, Bu Kang, Gil, Youn Kang, Jung, Lee, Jung-Gyu, Yop An, Jun, Ryoung Park, Kyoung, Lee, Youngjin, Jun Im, Young, Hyuck Lee, Jun, Hyun Eom, Soo
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726147/
https://ncbi.nlm.nih.gov/pubmed/26805589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19681
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы