Crystal structure of the catalytic domain of Clostridium perfringens neuraminidase in complex with a non-carbohydrate-based inhibitor, 2-(cyclohexylamino)ethanesulfonic acid

Anti-bacterial and anti-viral neuraminidase agents inhibit neuraminidase activity catalyzing the hydrolysis of terminal N-acetylneuraminic acid (Neu5Ac) from glycoconjugates and help to prevent the host pathogenesis that lead to fatal infectious diseases including influenza, bacteremia, sepsis, and...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Lee, Youngjin, Youn, Hyung-Seop, Lee, Jung-Gyu, An, Jun Yop, Park, Kyoung Ryoung, Kang, Jung Youn, Ryu, Young Bae, Jin, Mi Sun, Park, Ki Hun, Eom, Soo Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092837/
https://ncbi.nlm.nih.gov/pubmed/28315686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.03.064
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