Crystallization and preliminary X-ray crystallographic analysis of quinolinate phosphoribosyltransferase from porcine kidney in complex with nicotinate mononucleotide

Quinolinate phosphoribosyltransferase (QAPRTase) is a key enzyme in NAD biosynthesis; it catalyzes the formation of nicotinate mononucleotide (NAMN) from quinolinate and 5-phosphoribosyl-1-pyrophosphate. In order to elucidate the mechanism of NAMN biosynthesis, crystals of Sus scrofa QAPRTase (Ss-­Q...

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Hauptverfasser: Youn, Hyung-Seop, Kim, Mun-Kyoung, Kang, Gil Bu, Kim, Tae Gyun, An, Jun Yop, Lee, Jung-Gyu, Park, Kyoung Ryoung, Lee, Youngjin, Fukuoka, Shin-Ichi, Eom, Soo Hyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2012
Schlagworte:
Crystallization Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509970/
https://ncbi.nlm.nih.gov/pubmed/23192029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112040638
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