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Inhibiting the immunoproteasome exacerbates the pathogenesis of systemic Candida albicans infection in mice

Apart from its role in MHC class I antigen processing, the immunoproteasome has recently been implicated in the modulation of T helper cell differentiation under polarizing conditions in vitro and in the pathogenesis of autoimmune diseases in vivo. In this study, we investigated the influence of LMP...

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Publicat a:Sci Rep
Autors principals: Mundt, Sarah, Basler, Michael, Buerger, Stefanie, Engler, Harald, Groettrup, Marcus
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726078/
https://ncbi.nlm.nih.gov/pubmed/26776888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19434
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