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Trading off stability against activity in extremophilic aldolases

Understanding enzyme stability and activity in extremophilic organisms is of great biotechnological interest, but many questions are still unsolved. Using 2-deoxy-D-ribose-5-phosphate aldolase (DERA) as model enzyme, we have evaluated structural and functional characteristics of different orthologs...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Dick, Markus, Weiergräber, Oliver H., Classen, Thomas, Bisterfeld, Carolin, Bramski, Julia, Gohlke, Holger, Pietruszka, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725968/
https://ncbi.nlm.nih.gov/pubmed/26783049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17908
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