Redesigning Aldolase Stereoselectivity by Homologous Grafting

The 2-deoxy-d-ribose-5-phosphate aldolase (DERA) offers access to highly desirable building blocks for organic synthesis by catalyzing a stereoselective C-C bond formation between acetaldehyde and certain electrophilic aldehydes. DERA´s potential is particularly highlighted by the ability to catalyz...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Bisterfeld, Carolin, Classen, Thomas, Küberl, Irene, Henßen, Birgit, Metz, Alexander, Gohlke, Holger, Pietruszka, Jörg
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915726/
https://ncbi.nlm.nih.gov/pubmed/27327271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156525
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