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α-Synuclein and huntingtin exon 1 amyloid fibrils bind laterally to the cellular membrane
Fibrillar aggregates involved in neurodegenerative diseases have the ability to spread from one cell to another in a prion-like manner. The underlying molecular mechanisms, in particular the binding mode of the fibrils to cell membranes, are poorly understood. In this work we decipher the modality b...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4725933/ https://ncbi.nlm.nih.gov/pubmed/26757959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19180 |
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