Enhanced OCT4 transcriptional activity substitutes for exogenous SOX2 in cellular reprogramming

Adenoviral early region 1A (E1A) is a viral gene that can promote cellular proliferation and de-differentiation in mammalian cells, features required for the reprogramming of somatic cells to a pluripotent state. E1A has been shown to interact with OCT4, and as a consequence, to increase OCT4 transc...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Marthaler, Adele G., Adachi, Kenjiro, Tiemann, Ulf, Wu, Guangming, Sabour, Davood, Velychko, Sergiy, Kleiter, Ingo, Schöler, Hans R., Tapia, Natalia
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725906/
https://ncbi.nlm.nih.gov/pubmed/26762895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19415
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki