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Enhanced OCT4 transcriptional activity substitutes for exogenous SOX2 in cellular reprogramming
Adenoviral early region 1A (E1A) is a viral gene that can promote cellular proliferation and de-differentiation in mammalian cells, features required for the reprogramming of somatic cells to a pluripotent state. E1A has been shown to interact with OCT4, and as a consequence, to increase OCT4 transc...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4725906/ https://ncbi.nlm.nih.gov/pubmed/26762895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19415 |
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