One-pot system for synthesis, assembly, and display of functional single-span membrane proteins on oil–water interfaces

Single-span membrane proteins (ssMPs) represent approximately one-half of all membrane proteins and play important roles in cellular communications. However, like all membrane proteins, ssMPs are prone to misfolding and aggregation because of the hydrophobicity of transmembrane helices, making them...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Yunker, Peter J., Asahara, Haruichi, Hung, Kuo-Chan, Landry, Corey, Arriaga, Laura R., Akartuna, Ilke, Heyman, John, Chong, Shaorong, Weitz, David A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725511/
https://ncbi.nlm.nih.gov/pubmed/26721399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504992113
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