One-pot system for synthesis, assembly, and display of functional single-span membrane proteins on oil–water interfaces

Single-span membrane proteins (ssMPs) represent approximately one-half of all membrane proteins and play important roles in cellular communications. However, like all membrane proteins, ssMPs are prone to misfolding and aggregation because of the hydrophobicity of transmembrane helices, making them...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Yunker, Peter J., Asahara, Haruichi, Hung, Kuo-Chan, Landry, Corey, Arriaga, Laura R., Akartuna, Ilke, Heyman, John, Chong, Shaorong, Weitz, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2016
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725511/
https://ncbi.nlm.nih.gov/pubmed/26721399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504992113
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