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One-pot system for synthesis, assembly, and display of functional single-span membrane proteins on oil–water interfaces

Single-span membrane proteins (ssMPs) represent approximately one-half of all membrane proteins and play important roles in cellular communications. However, like all membrane proteins, ssMPs are prone to misfolding and aggregation because of the hydrophobicity of transmembrane helices, making them...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Yunker, Peter J., Asahara, Haruichi, Hung, Kuo-Chan, Landry, Corey, Arriaga, Laura R., Akartuna, Ilke, Heyman, John, Chong, Shaorong, Weitz, David A.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725511/
https://ncbi.nlm.nih.gov/pubmed/26721399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504992113
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