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Phosphorylation Increases Persistence Length and End-to-End Distance of a Segment of Tau Protein
Intrinsically disordered regions of proteins, which lack unique tertiary structure under physiological conditions, are enriched in phosphorylation sites and in significant local bias toward the polyproline II conformation. The overrepresented coincidence of this posttranslational regulatory signal a...
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| Publicat a: | Biophys J |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4725354/ https://ncbi.nlm.nih.gov/pubmed/26789759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.12.013 |
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