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Genes implicated in stem cell identity and temporal programme are directly targeted by Notch in neuroblast tumours

Notch signalling is involved in a multitude of developmental decisions and its aberrant activation is linked to many diseases, including cancers. One example is the neural stem cell tumours that arise from constitutive Notch activity in Drosophila neuroblasts. To investigate how hyperactivation of N...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Development
Egile Nagusiak: Zacharioudaki, Evanthia, Housden, Benjamin E., Garinis, George, Stojnic, Robert, Delidakis, Christos, Bray, Sarah J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists Ltd 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725341/
https://ncbi.nlm.nih.gov/pubmed/26657768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.126326
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