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Mi-2/NuRD complex protects stem cell progeny from mitogenic Notch signaling
To progress towards differentiation, progeny of stem cells need to extinguish expression of stem-cell maintenance genes. Failures in such mechanisms can drive tumorigenesis. In Drosophila neural stem cell (NSC) lineages, excessive Notch signalling results in supernumerary NSCs causing hyperplasia. H...
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| 出版年: | eLife |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6379090/ https://ncbi.nlm.nih.gov/pubmed/30694174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41637 |
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