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Genes implicated in stem cell identity and temporal programme are directly targeted by Notch in neuroblast tumours

Notch signalling is involved in a multitude of developmental decisions and its aberrant activation is linked to many diseases, including cancers. One example is the neural stem cell tumours that arise from constitutive Notch activity in Drosophila neuroblasts. To investigate how hyperactivation of N...

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Podrobná bibliografie
Vydáno v:Development
Hlavní autoři: Zacharioudaki, Evanthia, Housden, Benjamin E., Garinis, George, Stojnic, Robert, Delidakis, Christos, Bray, Sarah J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725341/
https://ncbi.nlm.nih.gov/pubmed/26657768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.126326
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