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Dual function of Bmpr1a signaling in restricting preosteoblast proliferation and stimulating osteoblast activity in mouse

Exogenous bone morphogenetic proteins (Bmp) are well known to induce ectopic bone formation, but the physiological effect of Bmp signaling on normal bone is not completely understood. By deleting the receptor Bmpr1a in osteoblast lineage cells with Dmp1-Cre, we observed a dramatic increase in trabec...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Lim, Joohyun, Shi, Yu, Karner, Courtney M., Lee, Seung-Yon, Lee, Wen-Chih, He, Guangxu, Long, Fanxin
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725340/
https://ncbi.nlm.nih.gov/pubmed/26657771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.126227
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