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Pyruvate Dehydrogenase Activity Is Decreased in the Peripheral Blood Mononuclear Cells of Patients with Sepsis. A Prospective Observational Trial

Rationale: Rodent studies have shown that pyruvate dehydrogenase (PDH) levels are low in sepsis. This may cause cells to shift to anaerobic metabolism, resulting in increased lactate production. Alterations in PDH during sepsis have never been studied in humans. Objectives: The objective of this pil...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Ann Am Thorac Soc
Main Authors: Nuzzo, Erin, Berg, Katherine M., Andersen, Lars W., Balkema, Julia, Montissol, Sophia, Cocchi, Michael N., Liu, Xiaowen, Donnino, Michael W.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Thoracic Society 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724894/
https://ncbi.nlm.nih.gov/pubmed/26356483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201505-267BC
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